Please find below the experimental data for our 2020 paper in PLOS Neglected Tropical Diseases titled: Taenia larvae possess distinct acetylcholinesterase profiles with implications for host cholinergic signalling
shared using a publicly accessible dropbox folder.
https://www.dropbox.com/sh/83scv79mom1ug21/AACh08I5c-fBIHLaaoeydLXRa?dl=0
Here is our lovely glossy report on the Imbizo from 2017-2019: Imbizo_report
Please find below the experimental data for our 2020 paper in PLOS Computational Biology titled: Chloride dynamics alter the input-output properties of neurons
shared using a publicly accessible dropbox folder.
https://www.dropbox.com/sh/1vprdumypkwjb1r/AACkMArWwN2XnVkajtAXroiDa?dl=0
Please find below all the data for our 2019 paper in Brain titled: Excitatory GABAergic signalling is associated with benzodiazepine resistance in status epilepticus
shared using a publicly accessible dropbox folder.
https://www.dropbox.com/sh/xrxy9k90t7jmtuy/AACxwHKghMLzAPldjIXJI7bza?dl=0
The third iteration of the IBRO-SIMONS Computational Neuroscience Imbizo – isiCNI2019 is currently underway in Muizenberg! Read more about it here: http://imbizo.africa/ or follow us Twitter
The goal of this 3 week summer school is to build computational neuroscience capacity in Africa by bringing together African and International students under the tutelage of world-leading experts in the field.
In December 2017 the lab helped organise and run the IBRO-UCT African Advanced School on Techniques in Neuroscience. The school was also supported by the Newton Fund. Many of the techniques established in the lab: whole-cell patch-clamp, interface local field potential recordings and Ca2+ imaging featured as part of the school. The full school report can be found here.
Jaideep Bains explaining the final subtleties of hippocampal circuitry.
Recording a ‘seizure’ in vitro!
Thijs Verhoog in action – the patch-clamp guru.
LFP recordings in hippocampal slices.
We are proud to announce that our paper describing the construction and performance of an open hardware ‘Picospritzer’ – Openspritzer is out. This was a collaborative effort with the Baden Lab who have a strong interest in open hardware and the development of neuroscience research capacity in Africa. Please find the paper and detailed build instructions here.
Designed for ease of use, robustness and low-cost, the “Openspritzer” is an open hardware “Picospritzer” as routinely used in biological labs around the world. The performance of Openspritzer and commercial alternatives is effectively indistinguishable.
The system is based on a solenoid valve connected to a pressure gauge. Control can be attained directly via an external TTL pulse or internally through an Arduino set by a rotary encoder. The basic setup can be put together for 3-400€, or substantially less if you are prepare to shop around.
After the smashing success of isiCNI2017 – the IBRO-SIMONS Computational Neuroscience Imbizo – is back for round 2 in January 2018. Please find more details at http://isicni.gatsby.ucl.ac.uk/. The application deadline is 15th August 2017.
GCAMP6S in an organotypic hippocampal slice.
This microscope is incredible!
Together with Tim Vogels, Peter Latham and Alex Antrobus we are organised a computational neuroscience school held in Muizenberg in January 2017. The goal of the school was to build computational neuroscience capacity in Africa by bringing together African and International students under the tutelage of world-leading experts in the field. We managed to attract some all star faculty for the first iteration of isiCNI.
If you are interested in what the school was like please see our report below: