Publications and Reviewed Preprints

2024

Selfe JS, Steyn TJS, Shorer EF, Burman RJ, Düsterwald KM, Kraitzick AZK, Abdelfattah AS, Schreiter ER, Newey SE, Akerman CJ, Raimondo JV, 2024, All-optical reporting of inhibitory receptor driving force in the nervous system. Nature Communications doi: 10.1101/2023.08.30.555464 pdf


2023

Burman RJ, Brodersen PJN, Raimondo JV, Sen A, Akerman CJ, 2023, Active cortical networks promote shunting fast synaptic inhibition in vivo. Neuron. 2023 Aug 29:S0896-6273(23)00586-X. doi: 10.1016/j.neuron.2023.08.005. pdf

de Lange A*, Tomes H*, Selfe JS, Prodjinotho UF, Verhoog, MB, Mahanty S, Smith K, Horsnell W, Sikasunge C, Prazeres da Costa C, Raimondo JV, 2023, Cestode larvae excite host neuronal circuits via glutamatergic signaling. eLife (reviewed preprint) doi: 10.7554/eLife.88174.1 link

Călin A, Waseem T, Raimondo JV, Newey SE, Akerman CJ, 2023, A genetically targeted ion sensor reveals distinct seizure-related chloride and pH dynamics in GABAergic interneuron populations. iScience. 2023 Mar 9;26(4):106363. doi: 10.1016/j.isci.2023.106363. pdf

Salile SS, Lee HJ, Alberts PSF, Abula T, Raimondo JV, Stafford GI, 2023, In vitro and in vivo anti-seizure activity of hydromethanolic extract and fractions of Pterolobium stellatum. J Ethnopharmacol. 2023 Mar 25;304:116073. doi: 10.1016/j.jep.2022.116073. pdf

Awala AN, Kauchali M, de Lange A, Higgitt ER, Mbangiwa T, Raimondo JV, Dangarembizi R, 2023, Mouse Organotypic Brain Slice Cultures: A Novel Model for Studying Neuroimmune Responses to Cryptococcal Brain Infections. Methods Mol Biol. 2023;2667:31-45. doi: 10.1007/978-1-0716-3199-7_3. pdf


2022

Steyn TJS*, Awala AN*, de Lange A, Raimondo JV, 2022, What Causes Seizures in Neurocysticercosis?, Epilepsy Currents, 15357597221137418. pdf

Currin CB, Raimondo JV, 2022, Computational models reveal how chloride dynamics determine the optimal distribution of inhibitory synapses to minimise dendritic excitability. PLoS Computational Biology. Sep 23;18(9):e1010534. doi: 10.1371/journal.pcbi.1010534. eCollection 2022 Sep. pdf

Burman RJ, Rosch RE, Wilmshurst JM, Sen A, Ramantani G, Akerman CJ, Raimondo JV, 2022, Why won’t it stop? The dynamics of benzodiazepine resistance in status epilepticus.  Nature Reviews Neurology. May 10. doi: 10.1038/s41582-022-00664-3. pdf

Idro R, Ogwang R, Barragan A, Raimondo JV, Masocha W, 2022, Neuroimmunology of Common Parasitic Infections in Africa. Frontiers in Immunolology. Feb 10;13:791488. doi: 10.3389/fimmu.2022.791488. pdf


2021

Van Belle s, de Lange A, Tomes H, Lucas R, Naidoo V, Raimondo JV, Peripheral Taenia infection increases immunoglobulins in the central nervous system. International Journal for Parasitology Jul;51(8):685-692. pdf

Burman RJ, Watson LM, Smith DC, Raimondo JV, Ballo R, Scholefield J, Cowley SA, Wood MJA, Kidson SH, Greenberg LJ., 2021, Molecular and electrophysiological features of spinocerebellar ataxia type seven in induced pluripotent stem cells. PLoS One 16(2):e0247434. doi: 10.1371/journal.pone.0247434. pdf


2020

de Lange A, Prodjinotho UF, Tomes H, Hagen J, Jacobs BA, Smith K, Horsnell W, Sikasunge C, Hockman D, Selkirk ME, Prazeres da Costa C, Raimondo JV, 2020,Taenia larvae possess distinct acetylcholinesterase profiles with implications for host cholinergic signalling. PLoS Neglected Tropical Diseases. 2020 Dec 21;14(12):e0008966. pdf

Currin CB, Trevelyan AJ, Akerman CJ, Raimondo JV, 2020, Chloride dynamics alter the input-output properties of neurons. PLoS Computational Biology 16(5):e1007932. pdf


2019

Burman RJ, Selfe JS, Lee JH, van den Berg M, Calin A, Codadu NK, Wright R, Newey SE, Parrish RR, Katz AA, Wilmshurst JM, Akerman CJ, Trevelyan AJ, Raimondo JV, 2019, Excitatory GABAergic signalling is associated with benzodiazepine resistance in status epilepticus. Brain. 2019 Sep 23. pii: awz283. doi: 10.1093/brain/awz283. pdf 

Currin CB, Khoza PN, Antrobus AD, Latham PE, Vogels TP, Raimondo JV, 2019, Think: Theory for Africa. PLoS Computational Biology Jul 11;15(7):e1007049. pdf

Raimondo JV, Dulla C. 2019, When a Good Cop Turns Bad: The Pro-Ictal Action of Parvalbumin Expressing Interneurons During Seizures. Epilepsy Currents. Jun 4:1535759719853548. pdf

Burman RJ, Raimondo JV, Jefferys JGR, Sen A, Akerman CJ, ,2019, The transition to status epilepticus: how the brain meets the demands of perpetual seizure activity. Seizure Sep 26. pii: S1059-1311(19)30292-4.  pdf

Codadu NK, Graham R, Burman RJ, Jackson-Taylor RT, Raimondo JV, Trevelyan AJ, Parrish RR, 2019, Divergent paths to seizure-like events. Physiological Reports Oct;7(19):e14226. pdf


2018

de Lange A, Mahanty S, Raimondo JV, 2018, Model systems for investigating disease processes in neurocysticercosis. Parasitology Nov 15:1-10. pdf

Düsterwald KM, Currin CB*, Burman RJ*, Akerman CJ, Kay AR, Raimondo JV, 2018, Biophysical models reveal the relative importance of transporter proteins and impermeant anions in chloride homeostasis. eLife 2018 Sep 27;7. pii: e39575 [*Co-authors] pdf

Dulla CG, Janigro D, Jiruska P, Raimondo JV, Ikeda A, Lin CCK, Goodkin HP, Galanopoulou AS, Bernard C, de Curtis M How do we use in vitro models to understand epileptiform and ictal activity? A report of the TASK 1‐WG 4 group of the ILAE/AES Joint Translational Task Force. Epilepsia Open, 2018, Nov 2;3(4):460-473 pdf


2017

Raimondo JV, Heinemann U, de Curtis M, Goodkin HP, Dulla C, Janigro D, Ikeda A, Lin C, Premysl J, Galanopoulou AS, Bernard C, Methodological standards for in vitro studies on normal or epileptic brain tissue. Epilepsia Nov;58 Suppl 4:40-52. pdf

Gurwitz* KT, Burman* RJ, Muragan* B, Ganief T, Garnett S, Soares NC, Raimondo JV, Blackburn JM, 2017 HIV-Tat treatment of human neurons in vitro over time: a model for the molecular pathology of HIV-associated neurocognitive disorders. Frontiers in Molecular Neuroscience May 29;10:163. [*Co-first Author]

Forman CJ, Tomes H, Mbobo B, Burman RJ, Jacobs M, Baden T, Raimondo JV, 2017 Openspritzer: an open hardware pressure ejection system for reliably delivering picolitre volumes. Scientific Reports May 19;7(1):2188. pdf

Wright R, Newey SE, Ilie A, Wefelmeyer W, Raimondo JV, Ginham RA, Mcllhinney J, Akerman CJ, 2017 Neuronal chloride regulation via KCC2 is modulated through a GABAB receptor protein complex Journal of Neuroscience May 31;37(22):5447-5462.


2016

Raimondo JV, Richards BA, Woodin MA, 2017 Neuronal chloride and excitability – the big impact of small changes. Current Opinion in Neurobiology 43:35-42 pdf

Raimondo JV, Tomes H, Irkle A, Kay L, Kellaway L, Markram H, Millar RP, Akerman CJ, 2016 Tight Coupling of Astrocyte pH Dynamics to Epileptiform Activity Revealed by Genetically-Encoded pH Sensors Journal of Neuroscience 36(26):7002-13 pdf


2015

Raimondo JV, Burman RJ, Katz AA, Akerman CJ, 2015 Ionic dynamics during seizures Frontiers in Cellular Neuroscience 9, 419 pdf


2014

Ellender TJ*, Raimondo JV*, Irkle A, Lamsa KP, Akerman CJ, 2014 Excitatory effects of parvalbumin-expressing interneurons sustain seizure activity via synchronous afterdischarges Journal of Neuroscience 34(46):15208-22 [*Co-first Author] pdf


2013

Raimondo JV, Joyce B, Kay L, Schlagheck T, Newey SE, Srinivas S, Akerman CJ, 2013 A genetically-encoded chloride and pH sensor for dissociating ion dynamics in the nervous system.  Frontiers in Cellular Neuroscience 7:202 pdf


2012

Raimondo JV, Kay L, Ellender TJ, Akerman CJ, 2012 Optogenetic silencing strategies differ in their effects on inhibitory synaptic transmission. Nature Neuroscience doi:10.1038/nn.3143. pdf

Raimondo JV, Markram H, Akerman CJ, 2012, Short-term ionic plasticity at GABAergic synapses.  Frontiers in Synaptic Neuroscience 4: 5. pdf

Raimondo JV, Irkle A, Wefelmeyer W, Newey SE, Akerman CJ, 2012 Genetically encoded proton sensors reveal activity-dependent pH changes in neurons.  Frontiers in Molecular Neuroscience 5: 68. pdf

Ilie A, Raimondo JV, Akerman CJ, 2012, Adenosine release during seizures attenuates GABAA receptor-mediated depolarization. Journal of Neuroscience 32(15):5321-32. pdf


2011

Wright R, Raimondo JV, Akerman CJ, 2011, Spatial and temporal dynamics in the ionic driving force for GABAA receptors. Journal of Neural Plasticity 2011:728395. pdf

Opie LH, Raimondo, JV, 2010, Cognitive function and memory loss, Living Longer, Living Better, Exploring the Heart-Mind Connection. Oxford University Press